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This lecture will describe how mutations in specific genes can cause neonatal diabetes and outline a new form of treatment.
Royal Society Croonian Lecture
Whether you eat a whole box of chocolates or fast for the day, the pancreatic beta-cells ensure that your blood glucose level remains relatively constant by regulating the release of insulin from the pancreatic beta-cells. Diabetes results when insulin release is inadequate and blood glucose levels chronically rise. This lecture will describe how a membrane protein pore known as the ATP-sensitive potassium (KATP) channel plays a vitally important role in regulating insulin secretion and show how mutations in KATP channel genes can cause neonatal diabetes, a rare genetic form of diabetes that develops soon after birth, and occasionally also developmental problems. It will also reveal how an understanding of KATP channel function has led to a new therapy for patients with neonatal diabetes.
Speaker(s): |
Professor Frances Ashcroft FRS | talks |
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Date and Time: |
29 May 2013 at 6:30 pm |
Duration: | 1 hour |
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Venue: |
The Royal Society |
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Tickets: |
FREE |
Available from: |
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Additional Information: |
Free admission, seats allocated on a first come, first served basis |
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