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From bench to bedside: KATP channels and neonatal diabetes

This lecture will describe how mutations in specific genes can cause neonatal diabetes and outline a new form of treatment.


Royal Society Croonian Lecture

Whether you eat a whole box of chocolates or fast for the day, the pancreatic beta-cells ensure that your blood glucose level remains relatively constant by regulating the release of insulin from the pancreatic beta-cells. Diabetes results when insulin release is inadequate and blood glucose levels chronically rise. This lecture will describe how a membrane protein pore known as the ATP-sensitive potassium (KATP) channel plays a vitally important role in regulating insulin secretion and show how mutations in KATP channel genes can cause neonatal diabetes, a rare genetic form of diabetes that develops soon after birth, and occasionally also developmental problems. It will also reveal how an understanding of KATP channel function has led to a new therapy for patients with neonatal diabetes.


Speaker(s):

Professor Frances Ashcroft FRS | talks

 

Date and Time:

29 May 2013 at 6:30 pm

Duration:

1 hour

 

Venue:

The Royal Society
6-9 Carlton House Terrace
London
SW1Y 5AG
+44 20 74 51 2500
http://www.royalsociety.org

More at The Royal Society...

 

Tickets:

FREE

Available from:

Additional Information:

Free admission, seats allocated on a first come, first served basis

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