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Live or die: the secret is in our genes

Join Adi and Ianin as they reveal details of their fascinating work.

All cells in the human body have the inbuilt capacity to commit suicide, or programmed cell death. This allows our body to control cell number and eliminate cells that are old, infected or damaged, but abnormalities in the control and execution of this process have been implicated in many diseases, including Alzheimer’s disease, autoimmune diseases and, above all, cancer. Iain and his team are attempting to redress the imbalance between promotion and inhibition of genetically determined programmed cell death, which is disrupted in cancer, by inducing ovarian cancer cells to commit suicide, either with the stimulus of viruses or chemotherapy. While Adi and her team have developed a fast, convenient and novel technique known as ’gene hunting’, which looks to ‘trap’ new genes involved in this process. They may use different approaches, but share a common goal, and here reveal details of their fascinating work and discuss the obstacles to be overcome in converting our increased understanding of cancer cell biology into novel therapies for cancer and other human diseases.

Adi Kimchi holds the Helena Rubinstein Professorial Chair in Cancer Research at the Weizmann Institute in Israel and has headed the Department of Molecular Genetics there since January 2001. Among the prizes and honours she has received are the Milstein Award for Excellency in Cytokine Research(1999), the Landau Award for Excellency in Biology and Biotechnology (1999) and the Seroussi Award for Cancer Research (2002).

Iain McNeish qualified in medicine from the University of Oxford in 1992. He completed his PhD in 1998, since when he has combined clinical practice in medical oncology with laboratory research, developing novel gene therapy strategies for the treatment of ovarian cancer. Since 2004, he has been a senior lecturer at Barts and the London School of Medicine.

This event is in association with Weizmann UK.


Prof Adi Kimchi | talks
Iain McNeish | talks


Date and Time:

23 November 2005 at 7:00 pm


2 hours



The Royal Institution of Great Britain
21 Albemarle Street
020 7409 2992

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£8, £5 for Ri Members and concessions

Available from:

www.rigb.org or phone 020 7409 2992

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